Regional score = size of largest nuclei/size of smallest nuclei
Scale ranges from 1-12. Most pleomorphic regions are in yellow.
Max pleomorphism value: 11

Proliferative activity of the invasive tumor is derived from mitotic figure counts. Mitotic figures detected are identified by a yellow box with a green box inset. Density is measured as total mitotic count divided by epithelial nuclei count in the invasive tumor area.

Exclusively measures how well epithelium forms tubules as average max and min tubule scores across the whole slide. This is an independently predictive feature that complements other tubule related features.

Sheet measurement exclusively measures sheet formation of the epithelium. This is an independently predictive feature that complements other tubule related features.

Measure of local nuclei organization, using detections of nuclei with only 2 nearby neighbors that can be linked in an efficient way. This is a particular measure of tubule formation (that complements the more general tubule formation feature) with well formed tubules having a high degree of nuclei with only 2 neighbors and poorly formed tubules having many nuclei with more than two neighbors or only one neighbor (incomplete tubule). The feature is computed as the proportion of such nuclei compared to total nuclei in invasive cancer.

Proportion of stroma in invasive cancer regions.
Measured ratio: 1.18